5707 N. 22nd Street
Tampa, FL 33610
P:813.272.2244
F:813.272.3766

Make Donation

Health Sciences
Resources
Basic InformationLatest News
Rogue Genes May Cause Some ALS CasesSticky Brain 'Plaques' Implicated in Alzheimer's AgainEven Your Bones Can Get Fat, Mouse Study SuggestsDoes a Low-Fat Dairy Habit Boost Parkinson's Risk?MicroRNA Biomarker Signature Identified for Allergic AsthmaHaywire Immune Cells May Help Cause BaldnessRegion in Brain Associated With Fear of Uncertain FutureBrain Scans Spot Where Fear and Anxiety LiveGene Therapy Might Someday Mend Badly Broken BonesLife Expectancy Slighter Shorter With Parkinson's, DementiaStudy Looks at Parkinson's Effect on Life SpanBody Cooling May Help Brain After Cardiac ArrestDo You Overeat? Your Brain Wiring May Be WhyGene Mutation May Speed Alzheimer's DeclineIs This Enzyme Making You Fat?Type 2 Diabetes May Be Bad for Brain Health'Brain Age' May Help Predict When You'll DieParkinson's Disease May Originate in Gut, Study SaysBlood-Based Genome Testing Feasible for Rapid Mutation AssayBlood Test May Gauge Death Risk After Surgery150-Year-Old Drug May Shorten 'Off' Time for Parkinson's PatientsBrain May Be Organized by Functions, Not Body PartsBody Temperature Might Give Clues to ComaCould Young Blood Boost the Aging Brain?A 'Brainwave' to Help Fight PTSDDizziness in Parkinson's May Be Due to Cerebral HypoperfusionMisunderstood Gene Tests May Lead to Unnecessary MastectomiesScientists Extend Lives of Mice With ALSFDA Approves 1st Direct-to-Consumer Genetic Risk TestsFDA OKs 1st At-Home Genetic Tests for 10 Disorders'SuperAgers' Have Less Whole-Brain Cortical Volume LossHigh Thyroid Hormone Levels Tied to Stiffer ArteriesBrain Changes May Mark Risk of Financial Exploitation in SeniorsRegular Exercise Slows Decline Even in Advanced Parkinson's DzBrain-Computer Link Restores Some Movement to Quadraplegic ManScientists Spot Gene for Rare Disorder Causing Deafness, BlindnessNew Technology Makes Gene Mapping Cheaper, Faster: StudyTurning Back the Aging Clock -- in MiceNew Parkinson's Drug Xadago ApprovedBrain 'Rewires' to Work Around Early-Life BlindnessBrain Training for Cancer Survivors' Nerve DamageASA: Vagus Nerve Stimulation May Enhance Stroke RecoveryGene Therapy: A Breakthrough for Sickle Cell Anemia?Gene Therapy Shows Promise for Aggressive LymphomaThe Brain Can Produce Its Own Sugar: ReportCould Parkinson's Disease Raise Stroke Risk?NHL Veterans Pledge Their Brains to ResearchMRIs Can Be Safe for People With Heart Devices …Scientists Shed Light on Possible Cause of NearsightednessBrain Chip Helps Paralyzed 'Type' With Their Mind
Links
Related Topics

Medical Disorders
Mental Disorders
Mental Health Professions

Vagus Nerve Might Play a Role in Fighting Inflammatory Disease


HealthDay News
Updated: Jan 11th 2017

new article illustration

WEDNESDAY, Jan. 11, 2017 (HealthDay News) -- Paired cervical vagus nerve stimulation (cVNS) with kilohertz electrical stimulation (KES) nerve block can preferentially activate efferent pathways, enhancing the anti-inflammatory benefits of cVNS, according to a study published online Jan. 5 in Scientific Reports.

Noting that the efferent pathway should be selectively activated in order to clinically implement anti-inflammatory therapy via cVNS, but that current implementations of cVNS activate both afferent and efferent pathways, Yogi A. Patel, from the Georgia Institute of Technology in Atlanta, and colleagues paired cVNS with KES nerve block to preferentially activate efferent pathways while blocking afferent pathways.

The researchers found that the anti-inflammatory effects of cVNS were enhanced with selective efferent cVNS. Afferent cVNS synchronously activated the greater splanchnic nerve in a dose-dependent manner. Complete afferent KES nerve block enabling efferent cVNS enhanced the anti-inflammatory benefits of cVNS; systemic inflammation was exacerbated by incomplete afferent KES nerve block.

"Overall, these data demonstrate the utility of paired efferent cVNS and afferent KES nerve block for achieving selective efferent cVNS, specifically as it relates to neuromodulation of systemic inflammation," the authors write.

Full Text